Silencing Lung Cancer Gene Disrupts Normal Genome

Research recently published in an issue of the American Association for Cancer Research has found that chemical modification, also known as hypermethylation, of a single gene in the lung may increase the progression and severity of lung cancer in a patient diagnosed with the condition.

The researchers found that this is often the case when a patient develops lung cancer after smoking, in other words “tobacco-mediated hypermethylation,” according to a Science Daily news article.

Through the development of these findings, it becomes much easier for scientists to treat lung cancer by reversing the process of “silencing” the gene, which has been identified as MTHFR, which upon modification induces a stronger surge of lung cancer development.

The study also noted that through the consumption of such dangerous carcinogens, such as tobacco smoke and potentially asbestos fibers, there may be the development of genome damage, which can cause mutations among genes, and eventually silencing them through chemical modification, which in turn also will cause the increase of lung cancer progression, according to scientists.

Mesothelioma Lung Cancer

Mesothelioma cancer is what the National Library of Medicine has deemed a “cancer of the tissue” and it effects the mesothelium “tissue that lines the lungs, stomach, heart and other organs.” The condition is often marked by several signs and symptoms, including the following, according to the National Cancer Institute (NCI):

* shortness of breath

* pain in the chest

* accumulation of fluid in the chest

* weight loss

* abdominal pain

* sweling in abdomen

* bowel obstruction

* blood clotting

* fever

* anemia

Litigation Involving Mesothelioma Cases

Individuals who have suffered from a mesothelioma diagnosis are encouraged to utilize a free legal consultation from an experienced mesothelioma attorney. It may be a necessary step to develop a mesothelioma lawsuit.

Developing mesothelioma-related litigation can provide monetary compensation for victims of the deadly disease.

Additionally, creating a mesothelioma lawsuit and obtaining money as an award for damages endured may assist a victim in paying for costly treatments. It is common that individuals who have mesothelioma cancer require the administration of chemotherapy, which can often cost several thousand dollars each session.

It is important that an individual who has been diagnosed with mesothelioma cancer know and understand their condition as it is often fatal and with a better understanding of the disease comes a prolonged fatal diagnosis. It is also in a victim’s best interest to learn about the array of treatment opportunities available to them. Many treatment options are available through participation in clinical trials sponsored by government agencies.

Leave a Reply

Your email address will not be published. Required fields are marked *